1. Tweetie – Tweetie for Mac

Tweetie App Screenshot Twitter Client For Mac Apple

You can download the free version, which is ad-supported, and try it out for as long as you want.

2. Twitterrific

Twitterrific is a fun application that lets you both read and publish posts or “tweets” to the Twitter community website. The application’s user interface is clean, concise and designed to take up a minimum of real estate on your Mac’s desktop.

To get started, visit the Twitter home page to sign up for an account for use with Twitterrific. Twitter accounts are free, take only minutes to set up and are a great way to stay connected with people around the globe.

3. Snitter: a desktop Twitter client

Snitter is made on the Adobe AIR platform which is both Mac OSX and Microsoft Windows compatible. There is currently a Linux version of Adobe AIR in alpha testing but some functionality is likely missing.

4. Canary

Welcome to the home page of the Alitheia Core, an integrated platform for large scale software engineering studies. Alitheia Core is free software, distributed under the 2-clause BSD license.

Alitheia Core works by importing the source code repository, mailing list archives and bug databases for a software project in a unified storage schema and running various analysis tools on the projects. You can find more about how Alitheia Core is designed in the documentation section of this site.

5. Twibble mobile

Twibble mobile is a fast and feature rich twitter client for Java enabled smartphones including Nokia and SonyEricsson. It supports video, pictures, GPS, Search, and more. The development of twibble for Blackberry has been discontinued since twitter now provides a client application for Blackberry devices. Current version is 1.1.3. (31 JUL 2010)

6.  Bluebird

Bluebird 1.0 Beta 3 is a beta release. It is for use by people not afraid of software that may have a few bugs in it. Due to a bug in previous builds of Bluebird, you must download it directly from the website — Sparkle updates will not work.

7. TweetDeck

TweetDeck is your personal real-time browser, connecting you with your contacts across Twitter, Facebook, MySpace, LinkedIn, Foursquare, Google Buzz and more.

8.  Nambu

Nambu is an elegant OS X desktop look and feel, inspired by iTunes 9.

We keep it simple, layering in extra features so they don’t get in the way. The more you explore Nambu the more you will find.

9. Syrinx

Syrinx is a fully customizable twitter client designed for Leopard (OS X 10.5+).  Syrinx is built from two ideals: efficient workflow and customization.

10. Pwitter

Pwitter is a simple and elegant Twitter client for Mac, that is written in Cocoa. The application runs on only Leopard at the moment. It seems to run fine on Snow Leopard too.

List of features:

General Twitter actions (download status updates, post statuses, post replies, send direct messages)

All communications with Twitter server is encrypted using HTTPS
Elegant and eye candy user interface with beautiful animation using Core Animation technology
Ability to filter the status view with a keyword

11. Tototl

A Lightweight Twitter Client for Mac OSX in Cocoa.

12. La Twi

LaTwit is a full featured client for Twitter and StatusNet (formerly known as Laconica) based social networking sites such as Twit Army and Identica. It also supports posting using Ping.fm.

LaTwit uses a unified timeline. This means that it will display all of your friends messages from multiple accounts and sites in a single consolidated view. It also has the option to show TwitPic image previews directly in the timeline, and has support for XMPP instant messages.

13. TwitterPod

TwitterPod is a Twitter client with message store capability. The messages by your friends and by yourself will all be stored and displayed on an easy-to-navigate window.

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